21 August 2024
Gross, R. S.; Thaweethai T.; Kleinman L. C.; et al.
Characterizing Long COVID in Children and Adolescents
JAMA. Published online 2024
https://doi.org/10.1001/jama.2024.12747
Keywords: ..
Conclusion: This study developed research indices for characterizing PASC in children and adolescents. Symptom patterns were similar but distinguishable between the 2 groups, highlighting the importance of characterizing PASC separately for these age ranges.
20 August 2024
Palmer, C.S., Perdios, C., Abdel-Mohsen, M. et al.
Non-human primate model of long-COVID identifies immune associates of hyperglycemia
Nat Commun 15, 6664 (2024)
https://doi.org/10.1038/s41467-024-50339-4
Keywords: Experimental models of disease, Metabolic disorders, SARS-CoV-2, Viral infection
Conclusion: ..
20 August 2024
University of Colorado at Boulder
The Invisible Damage: How COVID Rewires Our Brains
SciTechDaily – Health
https://scitechdaily.com/the-invisible-damage-how-covid-rewires-our-brains/
Keywords: Cortisol, COVID-19, Infectious Diseases, Long COVID, Neuroscience, University of Colorado at Boulder
Conclusion: ..
siehe auch
https://doi.org/10.1016/j.bbi.2024.07.034
19 August 2024
Mandhane P. J.
Notice of Retraction: Hahn LM, et al. Post–COVID-19 Condition in Children. JAMA Pediatrics. 2023;177(11):1226-1228.
JAMA Pediatr. 2024
https://doi.org/10.1001/jamapediatrics.2024.2996
Keywords: ..
Conclusion: ..
18 August 2024
Costantino, V., Grafton, Q., Kompas, T., Chu, L., Honeyman, D., Notaras, A. and MacIntyre, C.R.
The public health and economic burden of long COVID in Australia, 2022–24: a modelling study
Med J Aust, (2024) 221: 217-223
https://doi.org/10.5694/mja2.52400
Keywords: ..
Conclusion: Widespread SARS-CoV-2 infections in Australia mean that even a small proportion of infected people developing long COVID-related illness and disability could have important population health and economic effects. A paradigm shift is needed, from a sole focus on the immediate effects of coronavirus disease 2019 (COVID-19) to preventing and treating COVID-19 and treating long COVID, with implications for vaccine and antiviral policy and other mitigation of COVID-19.
15 August 2024
Leon Bhowmik, Md. Kutubul Hasan, Tahmina Akter Bristy, et al.
A Comparison of COVID-19 and post-COVID-19 Syndrome Among Symptomatic and Asymptomatic Patients in Bangladesh: A Retrospective Cohort Study
Heliyon, 2024, e36202
https://doi.org/10.1016/j.heliyon.2024.e36202.
Keywords: COVID-19, post-COVID-19, symptomatic, asymptomatic; risk factors
Conclusion: It was concluded that age, duration of illness, presence of respiratory distress, blood group, and disease severity are major risk factors for the development of post-COVID-19 syndrome.
15 August 2024
Johnson, C.
Study Finds Fatigued ME/CFS Brains Unable to Adapt to Cognitive Stress
healthrising.org/blog/2024/08/15/chronic-fatigue-syndrome-brain-cognitive-stressor/
Keywords: brain, cardiovascular, ion channels, neurovascular coupling
Conclusion: If the authors are correct then cognitive stress at least temporarily impairs the ability of the brain to speed resources (in the form of oxygen in the blood) to parts of the brain that need it – producing fatigue. (That sounds like postexertional malaise of the brain to me.)
13 August 2024
Nelson, C.
New Study Identifies Profile of Long Covid in Blood DNA
https://www.albanymed.org/news/study-identifies-profile-of-long-covid/
Keywords: ..
Conclusion: ..
11 August 2024
Van Tin, H.; Rethi, L.; Higa, S.; Kao, Y.-H.; Chen, Y.-J.
Spike Protein of SARS-CoV-2 Activates Cardiac Fibrogenesis through NLRP3 Inflammasomes and NF-κB Signaling.
Cells 2024, 13
https://doi.org/10.3390/cells13161331
Keywords: angiotensin-converting enzyme 2; cardiac fibroblasts; NLRP3 inflammasome; spike protein
Conclusion: S1 activates human CFs by priming NLRP3 inflammasomes through NF-κB signaling in an ACE2-dependent manner.
06 August 2024
Hammer, S., Monaca, C., Hoelz, A., Tannheimer, M., Huckels-Baumgart, S., Dornieden, K., Lüttel, D., Rall, M., & Müller, H.
“Im Endeffekt ist man auf sich allein gestellt.” Eine qualitative Analyse von Versorgungsbarrieren aus der Sicht Long COVID-Betroffener.
Zenodo 2024
https://doi.org/10.5281/zenodo.13088064
Keywords: Long COVID, Post COVID, Qualitative Forschung, Versorgungsforschung, Patientenperspektive
Conclusion: Um Menschen mit Long COVID eine adäquate medizinische und soziale Versorgung zu gewährleisten, sind eine zügige Aus- und Weiterbildung aller beteiligten Akteure sowie die Entwicklung und der Ausbau spezifischer Versorgungsangebote dringend erforderlich.
02 August 2024
Arlt, F. A.; Breuer, A.; Trampenau, E.; Boesl F.; Kirchner M.; Mertins, P.; Sánchez-Sendín, E.; Nasouti, M.; Mayrhofer, M.; Blüthner, M.; Endres, M.; Prüss, H.; Franke, C.
High serum prevalence of autoreactive IgG antibodies against peripheral nerve structures in patients with neurological post-COVID-19 vaccination syndrome
Front. Immunol. 2024, 15
https://doi.org/10.3389/fimmu.2024.1404800
Keywords: SARS-CoV-2 vaccination, COVID-19 vaccination, post-COVID-19 vaccination syndrome (PCVS), autoantibody, peripheral nerve, neurofilament autoantibodies, DFS-70
Conclusion: Our data suggest that autoantibodies against nervous system tissue could be relevant in PCVS patients. Autoantibodies against neurofilaments and cell nuclei with so far non-established links to this disease spectrum should be further elucidated to determine their biomarker potential.
31 Juli 2024
Proal, A.
Pathogen Reactiviation – Dr Amy Proal discusses
https://www.meresearch.org.uk/pathogen-reactiviation-dr-amy-proal-discusses/
Keywords: ..
Conclusion: ..
14 Juli 2024
Kratzer B, Gattinger P, Trapin D, et al.
Differential decline of SARS-CoV-2-specific antibody levels, innate and adaptive immune cells, and shift of Th1/inflammatory to Th2 serum cytokine levels long after first COVID-19
Allergy. 2024; 00: 1-20.
https://doi.org/10.1111/all.16210
Keywords: CD19+CD27+ B memory cells, COVID-19, leukopenia, long-term effect, recent thymic emigrants, SARS-CoV-2, specific antibody decline, Th1/Th2 cytokine shift
Conclusion: COVID-19 causes long-term reduction of innate and adaptive immune cells which is associated with a Th2 serum cytokine profile. This may provide an immunological mechanism for long-term sequelae after COVID-19.
11 Juli 2024
Bonzano, S.; Dallorto, E.; Bovetti, S.; Studer, M.; De Marchis, S.
Mitochondrial regulation of adult hippocampal neurogenesis: Insights into neurological function and neurodevelopmental disorders
Neurobiology of Disease, 2024, Vol. 199, 106604
https://doi.org/10.1016/j.nbd.2024.106604
Keywords: Mitochondria; Nr2f1; BBSOAS; Adult neural stem cells; Dentate gyrus
Conclusion: ..
12 Juni 2024
Hunt, K.; Maclean, A.; Locock, L.; O’Dwyer, C.; Nettleton, S.; Ziebland, S.; Wild, C.
Young adults’ experiences of biographical retrogression whilst living with long COVID
Sociology of Health & Illness 2024, 1–21.
https://doi.org/10.1111/1467-9566.13798
Keywords: biographical disruption, biographical retrogression, experience of illness, long COVID, young people
Conclusion: ..
31 Dezember 2023
Thoma, M.; Froehlich, L.; Hattesohl, D.B.R.; Quante, S.; Jason, L.A.; Scheibenbogen, C.
Why the Psychosomatic View on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Is Inconsistent with Current Evidence and Harmful to Patients
Medicina 2024, 60, 83.
https://doi.org/10.3390/medicina60010083
Keywords: myalgic encephalomyelitis; chronic fatigue syndrome; ME/CFS
Conclusion: False Psychosomatic Attributions on the Etiology of ME/CFS Hinder Adequate Patient Care.
Even though, in recent years, more and more healthcare practitioners view ME/CFS correctly as a somatic illness, there are still widespread views in the medical community of ME/CFS being a psychosomatic illness. These views are detrimental for affected patients as they can result in misdiagnosis and harmful therapies, such as GET, which can result in lasting worsening of symptoms. Moreover, false psychosomatic attributions lead to stigmatization. A correct biomedical understanding of ME/CFS in line with the current state of empirical evidence for treatment is, therefore, essential to providing adequate care to patients with ME/CFS.
Siehe auch Deutschen Gesellschaft für ME/CFS
https://www.mecfs.de/publikation-zur-psychosomatischen-sicht-auf-me-cfs/
6 April 2023
Grande, T.; Grande, B.; Gerner, P.; Hammer, S.; Stingl, M.; Vink, M.; Hughes, B.M.
The Role of Psychotherapy in the Care of Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Medicina 2023, 59, 719.
https://doi.org/10.3390/medicina59040719
Keywords: chronic fatigue syndrome; cognitive behavioral therapy; exercise; myalgic encephalomyelitis; pacing; psychotherapy; post-exertional malaise
Conclusion: There are several important and clear distinctions to be made between the pacing-led ME/CFS treatment approach that is outlined above and in many of the so-called ‘standard’ psychotherapeutic techniques that are often used with patients in health contexts. Challenging patients’ cognitions and stress limits is so elementary to routine psychotherapeutic/psychosomatic care that doubts about so-called ‘modifications’ in the sense of a ‘particularly careful’ approach to ME/CFS patients are, in our opinion, justified. However, conventional approaches involve unfulfillable therapeutic promises and the serious danger of deterioration. We, therefore, believe that a radical paradigm shift is needed in psychotherapy, health psychology, and other fields where psychosocial and behavioral support is provided to ill people, and which recognizes the somatic nature of ME/CFS and adjusts therapeutic goals accordingly. A particular imposition of ME/CFS is the phenomenon of PEM, whose control by means of pacing demands a high degree of vigilance, discipline, and renunciation from the patients. This means an enormous challenge for those affected, which is not encountered in this specific way in other chronic diseases. A psychotherapy that takes these realities into account and offers help in coping with them can make an important and, in our view, an indispensable contribution to the care of ME/CFS patients.
Siehe auch Deutschen Gesellschaft für ME/CFS (deutsche Übersetzung)
https://www.mecfs.de/puhttps://www.mecfs.de/wp-content/uploads/2024/02/Die-Rolle-der-Psychotherapie-in-der-Versorgung-von-Patienten-mit-MECFS_deutsch.pdfblikation-zur-psychosomatischen-sicht-auf-me-cfs/